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Dermatology Pocket Guide | Dosing, Workup, & Management | 5th Edition

The brand new 5th Edition has officially been released! It is now larger, easier to read, and comes in a high-gloss UV proctective finish!

Major new additions include:

• Updated wart treatments (bleomycin, 5-FU, & cimetidine)
• Pediatric dosing for DUPIXENT®
• New lab monitoring protocol for CellCept®

Prior additions include:

• SKYRIZI™ & ILUMYA™ added to biologics section

• EUCRISA® added to atopic dermatitis treatment ladder

• Costs of biologics updated

• Methotrexate pediatric dosing added

• PASI scores (70, 90, & 100) added to biologics section
• Biologics added (SILIQ® & TREMFYA®)
• Side effects of complex systemic medications organized by frequency
• Complex systemic medications table color-coded and easier to read for faster reference
• Erythroderma workup box added
• Qbrexza™ (glycopyrronium) added to hyperhidrosis section
• Tranexamic acid added to melasma section
• Mechanisms of complex systemic drugs elaborated
• Retinoid indications, lab workup, side effects, and mechanisms elaborated
• Bexarotine protocol elaborated
• Plaquenil updated laboratory monitoring
• New mnemonic for side effects of Vismodegib®
• Antihistamine dosing elaborated
• Serum free light chain assay added to monoclonal gammopathy workup
• Causes of drug-induced pemphigus
• Urticaria & angioedema workup refined & improved
• Generalized pruritus section improved
• Lupus section refined & improved
• Topical corticosteroid section improved
• Topical antiseptics improved
• Phototherapy dosing improved
• PDT protocol improved
• Laser absorption spectrum improved
• Color Coding throughout the card to make it easier to read and for faster reference

Complete contents are listed below:

General Dermatology:

• Atopic dermatitis: cytokines involved, treatment ladder & management for mild to severe atopic dermatitis.
• Acne: cytokines involved, subtypes & treatment ladder & management
• Rosacea: subtypes & treatment ladder & management
• Psoriasis: cytokines involved, treatment ladder for mild to severe psoriasis
• CTCL: workup, biopsy technique & treatment ladder & protocols
• Actinic Keratoses: monotherapy & combination therapy protocols
• Surgery: proper surgical margins, Langer's lines diagrams, 5-year survival data for melanoma depending on Breslow thickness
• Topical corticosteroids: most commonly used classes & formulations
• Topical steroid sparing agents: Tacrolimus & Pimecrolimus formulations
• Topical antibiotics for acne & rosacea, formulations & dosing
• Antihistamine options & dosing
• Antipruritic drugs & uses
• Cryotherapy protocols depending on lesion treated
• Melasma & Post-Inflammatory Hyperpigmentation treatment options
• Hyperhidrosis treatment options
• Vitiligo depigmentation options

Workup Boxes:

• Unknown Rash differential diagnosis
• Generalized pruritus workup
• Urticaria workup
• Angioedema workup
• Alopecia workup
• Erythroderma workup & differential diagnosis
• Pustular eruption workup & differential diagnosis
• Pyoderma Gangrenosum-like ulcers workup & differential diagnosis
• Biopsy sites for DIF
• Auto-immune Connective Tissue Diseases workups
• Cutaneous vasculitis (purpura) workup
• Urticarial vasculitis workup
• Retiform purpura workup
• Erythema nodosum workup
• Stevens Johnson Syndrome/Toxic Epidermal Necrolysis prognostication and treatment.

Anti-Microbials:

• Topical antifungals: best and most commonly used formulations, listed in progressive order.
• Systemic antifungals for tinea pedis & corporis: proper dosing, duration, and treatment outcomes
• Systemic antifungals for onychomycosis: dosing and duration
• Systemic antifungals for tinea capitis: dosing, duration, & selection based on organism
• Systemic treatment options, dosing, & duration for HSV infections (labialis, genital HSV, & Zoster)
• HSV prophylaxis
• Verruca Vulgaris & Condyloma Accuminata most common organisms and treatment ladder
• Molluscum contagiosum treatment ladder
• Antiparasitic topical and systemic treatment dosing & duration
• Systemic bacterial antibiotics most commonly used in dermatology & dosing
• Pre-op prophylaxis dosing & timing.
• Topical antibiotics for impetigo, wound infections, nasal MRSA eradication, pseudomonas, cutaneous MRSA, fungus, & yeast
• Sexually transmitted diseases, their presentations, first line treatments, & second line treatments.

Dermoscopy:

• Dermoscopy of melanoma-specific structures
• Dermoscopy of non-melanoma skin cancers (NMSC)

Complex Systemic Medications: This section includes the cost, dosing, lab monitoring, side effects, interactions with other medications, mechanism, & pregnancy category of the following commonly used complex systemic medications in Dermatology:

• Isotretinoin
• Acitretin
• Bexarotene
• Prednisone
• Methotrexate
• Azathioprine
• Cyclosporine
• Mycophenolate Mofetil
• Hydroxychloroquine
• Thalidomide
• Dapsone
• Colchicine
• Cyclophosphamide
• IVIG
• Rituximab
• Apremilast
• Etanercept
• Infliximab
• Adalimumab
• Ustekinumab
• Secukinumab
• Ixekizumab
• Brodalumab
• Guselkumab
• Omalizumab
• Dupilumab
• Targeted Immunotherapies: Ipilimumab, Prembrolizumab, Vismodegib, costs, side effects & mechanism

Physical Modalities in Dermatology:

• PUVA: ideal candidates, protocol, starting dose & dose escalation based on skin type, dosing of 8-methoxypsoralen, clearance schedule, maintenance schedule, adverse effects
• nbUVB: protocol, starting dose & dose escalation based on skin type
• Photodynamic Therapy (PDT): protocol & adjuvant therapy
• LASERs: the most commonly used lasers, their wavelengths, indications, & off-label uses. Also includes all the treatable chromophores, thermal relaxation times (TRT) & pulse duration required to destroy chromophores.

Drug Rash Section: The most common drug rashes and their culprit medications

• Exanthematous
• Urticarial
• Fixed drug eruption
• AGEP
• DRESS/DIHS
• SJS/TEN
• Photoallergic
• Vasculitic
• Linear Ig-A bullous dermatosis
• Pseudoporphyria
• Drug-induced systemic lupus
• Drug-induced SCLE
• Drug-induced psoriasis
• Drug-induced pemphigus